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Slow Cooker John Wayne Casserole: A Hearty, Southwestern Comfort Classic

  1. Brown the ground beef in a skillet over medium heat. Add the diced onion and cook until softened.
    Drain excess grease.
  2. Stir in the taco seasoning and diced tomatoes with green chilies. Simmer for a few minutes, then remove from heat.
  3. In a separate bowl, mix the softened cream cheese and sour cream until smooth and well combined.
  4. Lightly grease the slow cooker. Place pieces of biscuit dough along the bottom to form a base layer.
  5. Spread the seasoned beef mixture over the biscuit layer.
  6. Spoon the cream cheese mixture evenly over the beef layer.
  7. Sprinkle shredded cheese generously on top.
  8. Cover and cook on low for 4–5 hours or until the biscuit base is cooked through and the casserole is set.

Serving and Storage

Slow Cooker John Wayne Casserole is best served warm, straight from the crock pot.
It pairs well with a simple green salad, corn on the cob, or steamed vegetables to balance
its rich and hearty nature.

Leftovers can be stored in an airtight container in the refrigerator for up to 4 days.
Reheat individual portions in the microwave or warm larger portions in the oven.
While freezing is possible, the biscuit layer may soften slightly upon thawing.

Tips

  • Drain ground beef well to prevent excess liquid in the casserole.
  • Soften cream cheese fully for a smoother, creamier layer.
  • Avoid lifting the slow cooker lid during cooking to maintain even heat.
  • Use freshly shredded cheese for better melting.
  • If the center seems soft, cook an additional 20–30 minutes on low.

Variations

Spicy Version: Add extra jalapeños or a dash of hot sauce to the beef mixture.

Chicken John Wayne Casserole: Substitute ground beef with cooked, shredded chicken.

Low-Carb Option: Skip the biscuit layer and serve the casserole as a creamy beef bake.

Vegetable Boost: Add bell peppers, corn, or black beans for extra texture and nutrition.

Tex-Mex Twist: Top with crushed tortilla chips just before serving for added crunch.

Conclusion

Slow Cooker John Wayne Casserole is a satisfying, flavor-packed dish that delivers comfort in every bite.
The slow cooker method simplifies preparation while allowing the bold, creamy, and savory layers to
come together beautifully.

Whether you’re feeding a hungry family or preparing a make-ahead meal, this casserole is a dependable
recipe that combines ease, heartiness, and classic Southwestern flair.

FAQ

Why is it called John Wayne Casserole?
The name is linked to a recipe once associated with John Wayne, reflecting bold, hearty flavors.

Can I cook this on high?
Yes, but low heat is recommended for even cooking and a better biscuit texture.

Can I prepare it ahead of time?
You can assemble the layers in advance and refrigerate, then cook when ready.

What cheese works best?
Cheddar, Colby Jack, or a Mexican cheese blend all work well.

How do I know it’s done?
The casserole is ready when the biscuit base is cooked through and the center is set.

 

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